Information om | Engelska ordet ANTIRETROVIRALS

Exempel på hur man kan använda ANTIRETROVIRALS i en mening

• Enfuvirtide is indicated for the treatment of HIV-1 infection, in combination therapy with other antiretrovirals, in people where all other treatments have failed.
• It is typically used in combination with other antiretrovirals such as zidovudine, dolutegravir, and abacavir.
• Though initially developed as an independent antiviral treatment, it is most commonly used as a pharmacokinetic enhancer, in order to increase the plasma concentrations of other antiretrovirals.
• However, some research seem to suggest that immunosuppressive drugs and antiretrovirals may work synergistically to help both HIV viral loads/CD4 cell counts and prevent active rejection.
• Synergistic enhancers of antiretrovirals usually do not possess any antiretroviral properties alone, but when they are taken concurrently with antiretroviral drugs they enhance the effect of that drug.
• Darunavir may interact with medications commonly taken by people with HIV/AIDS such as other antiretrovirals, and antacids such as proton pump inhibitors and H2 receptor antagonists.
• However, this may be an underestimation as the clinical presentation has evolved with the use of antiretrovirals and may no longer align with initial descriptions of its symptomatology.
• Commonly prescribed medications for HIV, such as sulfonamides, anticonvulsants, antibacterials, antifungals, antimycobacterials, and, most notably, antiretrovirals, have an increased incidence of adverse cutaneous drug reactions in HIV-positive individuals, and even greater escalation of incidence in people with advanced disease progression in the form of AIDS.
• Also in 2001, Saad negotiated the "first-ever voluntary" licenses to manufacture generic versions of antiretrovirals (ARVs) to treat HIV, ending a "stand off" between the South African government and various multinational drug companies over anticompetitive activities.
• As of 2018, the Medicines Patent Pool holds licences for 13 HIV antiretrovirals, an HIV technology platform, 2 hepatitis C direct-acting antivirals and 1 investigational treatment for tuberculosis from patent holders AbbVie, Bristol-Myers Squibb, Gilead Sciences, MSD, ViiV Healthcare, Johns Hopkins University, the University of Liverpool, the US National Institutes of Health and Pharco Pharmaceuticals.
• The year before he had switched his medication from saquinavir to ritonavir to Crixivan, before near-fatal side effects convinced him to cease all antiretrovirals.
• Elevated concentrations of eluxadoline were observed with co-administration of inhibitors of the transporter protein OATP1B1, such as ciclosporin, gemfibrozil, certain antiretrovirals, rifampicin, and eltrombopag.

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