Information om | Engelska ordet BIOINFORMATIC

Exempel på hur man kan använda BIOINFORMATIC i en mening

• The number of non-coding RNAs within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest that there are thousands of non-coding transcripts.
• Based on bioinformatic and structural data, some have suggested that the α and β subunits may have catalytic activity similar to glycoamylases, and that missense mutations in these regions of the α subunit may contribute to the symptoms of XLG II.
• The biosynthetic pathway towards the aglycone core of nogalamycin has been determined by a combination of bioinformatic analysis and cloning of individual components of the biosynthetic pathway.
• Systems Biology in Reproductive Medicine is a peer-reviewed medical journal that covers the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatic, molecular, and biochemical, to address fundamental questions in reproductive biology, reproductive medicine, and translational research.
• While the function of the protein is not fully understood by the scientific community, bioinformatic tools have shown that the protein bares much similarity to zinc finger or transposase proteins.
• Some of genome browsers and bioinformatic databases have a list of structural variations in human genome with an emphasis on CNVs, and can show them in the genome browsing page, for example, UCSC Genome Browser.
• Next he found a way to connect Per Bak’s ideas of Self-Organized Criticality to proteins, which are networks compacted into globules by hydropathic forces, by using a new hydrophobicity scale (similar in precision to his dielectric scale of ionicity) invented in Brazil using bioinformatic methods on more than 5000 structures in the Protein Data Base.
• In this report in Nature Communications, they created a customized bioinformatic pipeline that detected twice as many BAP1 mutations than previous methods, they discovered new driver mutations in the splicing factors SF3A1, SRSF2, SRSF7 and RBM10, and they used new clonality algorithms to reveal that all of the canonical genomic aberrations in uveal melanoma occur relatively early in tumor evolution.
• Finally, the October 2016 preprint and subsequent paper demonstrate the bioinformatic reconstruction of the T cell receptor signaling pathway in Jurkat cells based on CROP-seq data.
• Since then, the McInerney research group has published several bioinformatic software programs including Clann: Software for inferring phylogenetic supertrees, Crann: Software for inferring selection, Modelgenerator: Amino acid and nucleotide substitution model selection, PutGaps: DNA gapped file from amino acid alignment, and TIGER: Identifying rapidly-evolving characters in evolutionary data.
• Research areas include biocatalysis and chemical analytics, enzyme technologies and protein engineering, microbial biotechnology, cell line development and epigenetic, bioinformatic and simulations, bioprocess technologies as well as bioeconomy and environmental biotechnology.

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