Information om | Engelska ordet HPSCS

Exempel på hur man kan använda HPSCS i en mening

• Development of skeletal muscle organoids to model neuromuscular disorders and muscular dystrophies; an in vitro technique in which human pluripotent stem cells (hPSCs) are differentiated into functional 3D human skeletal muscle organoid (hSkMOs); hPSCs were guided towards the paraxial mesodermal lineage which then gives rise to myogenic pregenitor cells and myoblasts in well plates with no scaffold; organoids were round, uniformly sized, and exhibited homogeneous morphology upon full development and were shown to successfully model muscle development and regeneration.
• To generate organoids, human pluripotent stem cells (hPSCs) are allowed to aggregate into embryoid bodies (EBs) in low attachment plates (in suspension), which are then cultivated in a rotating bioreactor with lineage specific factors to promote cell amplification, growth and differentiation.

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