Synonymer & Information om | Engelska ordet HYPOXANTHINE

Exempel på hur man kan använda HYPOXANTHINE i en mening

• These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid.
• HGPRT is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate.
• It is the ribonucleotide of hypoxanthine and the first nucleotide formed during the synthesis of purine nucleotides.
• HAT Medium (hypoxanthine-aminopterin-thymidine medium) is a selection medium for mammalian cell culture, which relies on the combination of aminopterin, a drug that acts as a powerful folate metabolism inhibitor by inhibiting dihydrofolate reductase, with hypoxanthine (a purine derivative) and thymidine (a deoxynucleoside) which are intermediates in DNA synthesis.
• PNP metabolizes inosine into hypoxanthine and guanosine into guanine, in each case creating ribose phosphate.
• They discovered that this rare genetic disease, Lesch–Nyhan syndrome, was due to a profound deficiency of an enzyme known as hypoxanthine guanine phosphoribosyltransferase, or HGPRT, for short.
• These enzymes found in the glycosome to help with synthesis are guanine and adenine phosphoribosyl transferase, hypoxanthine, and xanthine pho tran.
• The initial step of AMP degradation is the conversion to xanthine into alternative routes, xanthosine or hypoxanthine.
• Flow Injection methods applied to the determination of amino acids (histidine, L-lysine and tyrosine), DNA/RNA, formaldehyde, histamine, hypoxanthine, polycyclic aromatic hydrocarbons, diarrheic shellfish poisoning, paralytic shellfish poisoning, succinate/glutamate, trimethylamine/ total volatile basic nitrogen, total lipid hydroperoxides, total volatile acids, uric acid, vitamin B12, silver, aluminium, arsenic, boron, calcium, cadmium, cobalt, chromium, copper, iron, gallium, mercury, indium, lithium, manganese, molibdenum, nickel, lead, antimony, selenium, tin, strontium, thallium, vanadium, zinc, nitrate/nitrite, phosphorus/phosphate and silicate.
• ADAR enzymes bind to double-stranded RNA (dsRNA) and convert adenosine to inosine (hypoxanthine) by deamination.
• "Using HPLC to determine quantity of hypoxanthine, xanthine, uracil, and uridyl in Di Long", Journal of Traditional Chinese Medicine Material, 1996;19(12):625-627.
• Leteprinim (Neotrofin, AIT-082) is a hypoxanthine derivative drug with neuroprotective and nootropic effects.
• However, normal human and mouse cells can still multiply as they can utilize hypoxanthine and thymidine present in the medium through a salvage pathway, which ordinarily recycles the purines and pyrimidines produced from degradation of nucleic acids.
• The G-quartet typically binds monovalent cations such as potassium, while other bases can bind numerous other ligands such as hypoxanthine in a U-U-C-U quadruplex.
• This protein can degrade all purine nucleosides (including xanthosine) except adenosine, deoxyadenosine, hypoxanthine arabinoside.
• However, DNA deoxyinosine glycosylase activity, the removal of a hypoxanthine base, is observed within the uracil DNA glycosylase superfamily.

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