Information om | Engelska ordet INSERTIONAL

Exempel på hur man kan använda INSERTIONAL i en mening

• Achilles tendon injuries can be separated into insertional tendinopathy (20%–25% of the injuries), midportion tendinopathy (55%–65%), and proximal musculotendinous junction (9%–25%) injuries, according to the location of pain.
• A posterior calcaneal spur is often large and palpable through the skin and may need to be removed as part of the treatment of insertional Achilles tendonitis.
• Historically, lentiviral vectors included strong viral promoters which had a side effect of insertional mutagenesis, nuclear DNA mutations that effect the function of a gene.
• While MA, IN, VPR, and cPPT had been previously implicated as factors in HIV's ability to target non-dividing cells, CA has been shown to be the dominant determinant of retrovirus infectivity in non-dividing cells, which is key in helping to avoid insertional mutagenesis in lentiviral gene therapy.
• Fli-1 is activated through retroviral insertional mutagenesis in 90% of F-MuLV-induced erythroleukemias.
• Insertion of foreign DNA into the MCS located within lacZ causes insertional inactivation of this gene at the N-terminal fragment of beta-galactosidase and abolishes intra-allelic complementation.
• AAV also has little risk for insertional mutagenesis, a common problem when dealing with viral vectors, as its transgenes are normally expressed episomally.

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